Gangrene refers to the death of body tissue due to a lack of blood flow or a bacterial infection. Gangrene most commonly affects the extremities, including your toes, fingers and limbs, but it can also occur in your muscles and internal organs.
Your chances of developing gangrene are higher if you have an underlying condition that can damage your blood vessels and affect blood flow, such as diabetes or atherosclerosis.
Treatments for gangrene include surgery to remove dead tissue, antibiotics and other approaches. The prognosis for recovery is better if gangrene is identified early and treated quickly.
Symptoms
When gangrene affects your skin, signs and symptoms may include:
- Skin discoloration — ranging from pale to blue, purple, black, bronze or red, depending on the type of gangrene you have
- Severe pain followed by a feeling of numbness
- A foul-smelling discharge leaking from a sore
If you have a type of gangrene that affects tissues beneath the surface of your skin, such as gas gangrene or internal gangrene, you may notice that:
1) The affected tissue is swollen and painful
2) You're running a fever and feel unwell
A condition called septic shock can occur if a bacterial infection that originated in the gangrenous tissue spreads throughout your body. Signs and symptoms of septic shock include:
a) Low blood pressure
b) A body temperature greater than 100.4 F (38 C) or lower than 96.8 F (36 C)
c) Rapid heart rate
d) Lightheadedness
e) Shortness of breath
f) Confusion

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